検索対象:     
報告書番号:
※ 半角英数字
 年 ~ 
 年

Safety operation of chromatography column system with discharging hydrogen radiolytically generated

クロマトグラフィカラムからの放射線分解ガスの排出挙動

渡部 創; 佐野 雄一; 野村 和則; 駒 義和; 岡本 芳浩

Watanabe, So; Sano, Yuichi; Nomura, Kazunori; Koma, Yoshikazu; Okamoto, Yoshihiro

In the extraction chromatography system, accumulation of hydrogen gas in the chromatography column is suspected to lead the fire or explosion. In order to prevent the hazardous accidents, it is necessary to evaluate behaviors of gas radiolytically generated inside the column. In this study, behaviors of gas inside the extraction chromatography column were investigated through experiments and Computation Fluid Dynamics (CFD) simulation. N$$_{2}$$ gas once accumulated as bubbles in the packed bed was hardly discharged by the flow of mobile phase. However, the CFD simulation and X-ray imaging on $$gamma$$-ray irradiated column revealed that during operation the hydrogen gas generated in the column was dissolved into the mobile phase without accumulation and discharged.

Access

:

- Accesses

InCites™

:

Altmetrics

:

[CLARIVATE ANALYTICS], [WEB OF SCIENCE], [HIGHLY CITED PAPER & CUP LOGO] and [HOT PAPER & FIRE LOGO] are trademarks of Clarivate Analytics, and/or its affiliated company or companies, and used herein by permission and/or license.