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Journal Articles

Conformational dynamics of a multidomain protein by neutron scattering and computational analysis

Nakagawa, Hiroshi; Saio, Tomohide*; Nagao, Michihiro*; Inoue, Rintaro*; Sugiyama, Masaaki*; Ajito, Satoshi; Tominaga, Taiki*; Kawakita, Yukinobu

Biophysical Journal, 120(16), p.3341 - 3354, 2021/08

 Times Cited Count:1 Percentile:12.07(Biophysics)

A multi-domain protein can have various conformations in solution. Interactions with other molecules result in the stabilization of one of the conformations and change in the domain dynamics. SAXS, a well-established experimental technique, can be employed to elucidate the conformation of a multi-domain protein in solution. NSE spectroscopy is a promising technique for recording the domain dynamics in nanosecond and nanometer scale. Despite the great efforts, there are still under development. Thus, we quantitatively removed the contribution of diffusion dynamics and hydrodynamic interactions from the NSE data via incoherent scattering, revealing the differences in the domain dynamics of the three functional states of a multi-domain protein, MurD. The differences among the three states can be explained by two domain modes.

Journal Articles

Relevance of hydrogen bonded associates to the transport properties and nanoscale dynamics of liquid and supercooled 2-propanol

Zhai, Y.*; Luo, P.*; Nagao, Michihiro*; Nakajima, Kenji; Kikuchi, Tatsuya*; Kawakita, Yukinobu; Kienzle, P. A.*; Z, Y.*; Faraone, A.*

Physical Chemistry Chemical Physics, 23(12), p.7220 - 7232, 2021/03

 Times Cited Count:3 Percentile:36.34(Chemistry, Physical)

Journal Articles

A Telescoping view of solute architectures in a complex fluid system

Motokawa, Ryuhei; Kobayashi, Toru; Endo, Hitoshi; Mu, J.*; Williams, C. D.*; Masters, A. J.*; Antonio, M. R.*; Heller, W. T.*; Nagao, Michihiro*

ACS Central Science, 5(1), p.85 - 96, 2019/01

 Times Cited Count:43 Percentile:87.67(Chemistry, Multidisciplinary)

Journal Articles

Two inherent crossovers of the diffusion process in glass-forming liquids

Kofu, Maiko; Faraone, A.*; Tyagi, M.*; Nagao, Michihiro*; Yamamuro, Osamu*

Physical Review E, 98(4), p.042601_1 - 042601_6, 2018/10

 Times Cited Count:4 Percentile:38.98(Physics, Fluids & Plasmas)

Journal Articles

Neutron scattering studies on short- and long-range layer structures and related dynamics in imidazolium-based ionic liquids

Nemoto, Fumiya*; Kofu, Maiko; Nagao, Michihiro*; Oishi, Kazuki*; Takata, Shinichi; Suzuki, Junichi*; Yamada, Takeshi*; Shibata, Kaoru; Ueki, Takeshi*; Kitazawa, Yuzo*; et al.

Journal of Chemical Physics, 149(5), p.054502_1 - 054502_11, 2018/08

 Times Cited Count:18 Percentile:72.98(Chemistry, Physical)

Journal Articles

Neutron polarization analysis for biphasic solvent extraction systems

Motokawa, Ryuhei; Endo, Hitoshi*; Nagao, Michihiro*; Heller, W. T.*

Solvent Extraction and Ion Exchange, 34(5), p.399 - 406, 2016/07

 Times Cited Count:4 Percentile:16.91(Chemistry, Multidisciplinary)

Journal Articles

Installation of JMTR core management system

Imaizumi, Tomomi; Ide, Hiroshi; Naka, Michihiro; Komukai, Bunsaku; Nagao, Yoshiharu

UTNL-R-0483, p.10_2_1 - 10_2_8, 2013/03

no abstracts in English

JAEA Reports

Conceptual design of multipurpose compact research reactor; Annual report FY2010 (Joint research)

Imaizumi, Tomomi; Miyauchi, Masaru; Ito, Masayasu; Watahiki, Shunsuke; Nagata, Hiroshi; Hanakawa, Hiroki; Naka, Michihiro; Kawamata, Kazuo; Yamaura, Takayuki; Ide, Hiroshi; et al.

JAEA-Technology 2011-031, 123 Pages, 2012/01


The number of research reactors in the world is decreasing because of their aging. However, the planning to introduce the nuclear power plants is increasing in Asian countries. In these Asian countries, the key issue is the human resource development for operation and management of nuclear power plants after constructed them, and also the necessity of research reactor, which is used for lifetime extension of LWRs, progress of the science and technology, expansion of industry use, human resources training and so on, is increasing. From above backgrounds, the Neutron Irradiation and Testing Reactor Center began to discuss basic concept of a multipurpose low-power research reactor for education and training, etc. This design study is expected to contribute not only to design tool improvement and human resources development in the Neutron Irradiation and Testing Reactor Center but also to maintain and upgrade the technology on research reactors in nuclear power-related companies. This report treats the activities of the working group from July 2010 to June 2011 on the multipurpose low-power research reactor in the Neutron Irradiation and Testing Reactor Center and nuclear power-related companies.

Journal Articles

Development on in-reactor observation system using cherenkov light, 2

Takemoto, Noriyuki; Tsuchiya, Kunihiko; Nagao, Yoshiharu; Kitagishi, Shigeru; Naka, Michihiro; Kimura, Akihiro; Sano, Tadafumi*; Unesaki, Hironobu*; Yoshimoto, Takaaki*; Nakajima, Ken*; et al.

KURRI Progress Report 2010, P. 204, 2011/10

no abstracts in English

Journal Articles

Development on in-reactor observation system using cherenkov light

Tsuchiya, Kunihiko; Kitagishi, Shigeru; Nagao, Yoshiharu; Takemoto, Noriyuki; Naka, Michihiro; Kimura, Akihiro; Sano, Tadafumi*; Unesaki, Hironobu*; Yoshimoto, Takaaki*; Nakajima, Ken*; et al.

KURRI Progress Report 2009, P. 196, 2010/10

no abstracts in English

Journal Articles

Investigation of optimization on in-core fuel management with high reactor-availability-factor of JMTR

Takemoto, Noriyuki; Naka, Michihiro; Nagao, Yoshiharu

Proceedings of 12th International Group on Research Reactors (12th IGORR) (USB Flash Drive), 11 Pages, 2009/10

no abstracts in English

JAEA Reports

Investigation on high availability-factor achievement of JMTR; How to achieve 60% availability-factor

Takemoto, Noriyuki; Izumo, Hironobu; Inoue, Shuichi; Abe, Shinichi; Naka, Michihiro; Akashi, Kazutomo; Omi, Masao; Miyazawa, Masataka; Baba, Osamu*; Nagao, Yoshiharu

JAEA-Review 2008-051, 36 Pages, 2008/10


The JMTR has been refurbished to restart operation in FY2011. The restarted JMTR plays roles of (1) measures for long-term operation of light water reactors, (2) improvement in scientific technique, (3) increase of industrial use, (4) training of human resources, etc. It is needed to operate the restarted JMTR safety and stably and maintain high available factor (50$$sim$$70%) because of increasing of irradiation utilization demand. In this report, measures for training of reactor operators, organization for operating, etc were proposed to operate reactor safety and smoothly. And also reactor operation procedure was examined to improve available factor up to world level for materials testing reactor. As a result, it was turned out to be possible to realize stably 210 days operation per year (available factor: 60%).

JAEA Reports

Improvement of JMTR core management system; Applicability of SRAC2006 code system to JMTR core management system

Gorai, Shigeru; Naka, Michihiro; Izumo, Hironobu; Nagao, Yoshiharu; Kawamura, Hiroshi

JAEA-Technology 2008-040, 17 Pages, 2008/06


Various projects for improvement of JMTR are being carried out with the aim to re-start in FY2011. In the projects, it is planned to improve the JMTR core management system to execute neutronic calculations. The JMTR core management system is based on SRAC code system on mainframe, it is expected to improve the JMTR core management system by means of conversion from SRAC code system to the newest SRAC2006 code system on UNIX. Therefore neutronic calculations for JMTR using SRAC2006 code system were executed in order to estimate applicability and effectiveness of SARC2006 code system to the JMTR core management system.

Journal Articles

Temperature-dependent nano-scale dynamics of PVA physical gel

Takahashi, Nobuaki; Nishida, Koji*; Inoue, Rintaro*; Ogawa, Hiroki*; Kanaya, Toshiji*; Nagao, Michihiro*

NSL News Letter, 2007-4, p.155 - 157, 2007/04

We have studied dynamics of poly(vinyl alcohol) (PVA) gel in a mixture of deuterated dimethyl sulfoxide (DMSO-d$$_{6}$$) and D$$_{2}$$O (60/40 by volume) during heating process from 25$$^{circ}$$C to 80$$^{circ}$$C using neutron spin-echo (NSE) techniques.

Journal Articles

Dynamic and static fluctuations in polymer gels studied by neutron spin-echo

Kanaya, Toshiji*; Takahashi, Nobuaki; Nishida, Koji*; Seto, Hideki*; Nagao, Michihiro*; Takeda, Takayoshi*

Physica B; Condensed Matter, 385-386(1), p.676 - 681, 2006/11

 Times Cited Count:13 Percentile:52.43(Physics, Condensed Matter)

We report neutron spin-echo measurements on three types of poly(vinyl alcohol) (PVA) gels. The first is PVA gel in a mixture of dimethyl sulfoxide (DMSO) and water with volume ratio 60/40, the second is PVA gel in an aqueous borax solution and the third is chemically cross-linked PVA gel. The observed normalized intermediate scattering functions I(Q,t)/I(Q,0) were very different among them. The I(Q,t)/I(Q,0) of the first and third gels showed a non-decaying component in addition to a decaying component, but the second one did not have the non-decaying one. This clearly indicates that the fluctuations in the first and third PVA gels consist of static and dynamic fluctuations whereas the second PVA gel does include only the dynamic fluctuations. The dynamic and static fluctuations of the PVA gels were analyzed in terms of a restricted motion in the gel network and the Zimm motion, respectively.

Journal Articles

Neutron spin-echo studies on poly(vinyl alcohol) gels during melting process

Takahashi, Nobuaki; Nishida, Koji*; Tsubouchi, Tsuyoshi*; Ogawa, Hiroki*; Inoue, Rintaro*; Kanaya, Toshiji*; Nagao, Michihiro*

ISSP Activity Report on Neutron scattering Research; Experimental Reports (CD-ROM), 13, 2 Pages, 2006/00

no abstracts in English

Journal Articles

Neutron spin-echo studies on crossover from single chain motion to collective dynamics

Kanaya, Toshiji; Takahashi, Nobuaki; Inoue, Rintaro*; Matsuba, Go*; Nishida, Koji*; Nagao, Michihiro*

ISSP Activity Report on Neutron scattering Research; Experimental Reports (CD-ROM), 13, 1 Pages, 2006/00

JAEA Reports

Thermal hydraulic analysis of the JMTR improved LEU-core

Tabata, Toshio; Nagao, Yoshiharu; Komukai, Bunsaku; Naka, Michihiro; Takeda, Takashi*; Fujiki, Kazuo

JAERI-Tech 2002-100, 108 Pages, 2003/01


After the investigation of the new core arrangement for the JMTR reactor in order to enhance the fuel burn-up and consequently extend the operation period, the "improved LEU core" that utilized 2 additional fuel elements instead of formerly installed reflector elements, was adopted. This report describes the results of the thermal-hydraulic analysis of the improved LEU core as a part of safety analysis for the licensing. The analysis covers steady state, abnormal operational transients and accidents, which were described in the annexes of the licensing documents as design bases events. Calculation conditions for the computer codes were conservatively determined based on the neutronic analysis results and others. The results of the analysis, that revealed the safety criteria were satisfied on the fuel temperature, DNBR and primary coolant temperature, were used in the licensing. The operation license of the JMTR with the improved LEU core was granted in March 2001, and the reactor operation with new core started in November 2001 as 142nd operation cycle.

JAEA Reports

Neutronics analysis of the improved LEU core in JMTR

Komukai, Bunsaku; Naka, Michihiro; Tabata, Toshio; Nagao, Yoshiharu; Takeda, Takashi*; Fujiki, Kazuo

JAERI-Tech 2002-067, 75 Pages, 2002/08


no abstracts in English

Journal Articles

Feasibility study for improvement of efficient irradiation with LEU core in JMTR

Naka, Michihiro; Nagao, Yoshiharu; Komukai, Bunsaku; Tabata, Toshio

Proceedings of 7th Meeting of the International Group on Research Reactors (IGORR-7) (CD-ROM), 7 Pages, 1999/10

no abstracts in English

29 (Records 1-20 displayed on this page)