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Wakai, Eiichi; Watanabe, Kazuyoshi*; Ito, Yuzuru*; Suzuki, Akihiro*; Terai, Takayuki*; Yagi, Juro*; Kondo, Hiroo; Kanemura, Takuji; Furukawa, Tomohiro; Hirakawa, Yasushi; et al.
Plasma and Fusion Research (Internet), 11, p.2405112_1 - 2405112_4, 2016/11
Wakai, Eiichi; Kondo, Hiroo; Sugimoto, Masayoshi; Fukada, Satoshi*; Yagi, Juro*; Ida, Mizuho; Kanemura, Takuji; Furukawa, Tomohiro; Hirakawa, Yasushi; Watanabe, Kazuyoshi; et al.
Purazuma, Kaku Yugo Gakkai-Shi, 88(12), p.691 - 705, 2012/12
no abstracts in English
Kondo, Hiroo; Furukawa, Tomohiro; Hirakawa, Yasushi; Nakamura, Kazuyuki; Ida, Mizuho; Watanabe, Kazuyoshi; Kanemura, Takuji; Wakai, Eiichi; Horiike, Hiroshi*; Yamaoka, Nobuo*; et al.
Nuclear Fusion, 51(12), p.123008_1 - 123008_12, 2011/12
Times Cited Count：39 Percentile：82.79(Physics, Fluids & Plasmas)The Engineering Validation and Engineering Design Activity (EVEDA) for the International Fusion Materials Irradiation Facility (IFMIF) is proceeded as one of the ITER Broader Approach (BA) activities. The EVEDA Li test loop (ELTL) is aimed at validating stability of the Li target and feasibility of a Li purification system as the key issues. In this paper, the design of the ELTL especially of a target assembly in which the Li target is produced by the contraction nozzle is presented.
Nakamura, Kazuyuki; Furukawa, Tomohiro; Hirakawa, Yasushi; Kanemura, Takuji; Kondo, Hiroo; Ida, Mizuho; Niitsuma, Shigeto; Otaka, Masahiko; Watanabe, Kazuyoshi; Horiike, Hiroshi*; et al.
Fusion Engineering and Design, 86(9-11), p.2491 - 2494, 2011/10
Times Cited Count：10 Percentile：60.68(Nuclear Science & Technology)In IFMIF/EVEDA, tasks for lithium target system are shared to 5 validation tasks (LF1-5) and a design task (LF6). The purpose of LF1 task is to construct and operate the EVEDA lithium test loop, and JAEA has a main responsibility to the performance of the Li test loop. LF2 is a task for the diagnostics of the Li test loop and IFMIF design. Basic research for the diagnostics equipment has been completed, and the construction for the Li test loop will be finished before March in 2011. LF4 is a task for the purification systems with nitrogen and hydrogen. Basic research for the purification equipment has been completed, and the construction of the nitrogen system for the Li test loop will be finished before March in 2011. LF5 is a task for the remote handling system with the target assembly. JAEA has an idea to use the laser beam for cutting and welding of the lip part of the flanges. LF6 is a task for the design of the IFMIF based on the validation experiments of LF1-5.
Ida, Mizuho; Fukada, Satoshi*; Furukawa, Tomohiro; Hirakawa, Yasushi; Horiike, Hiroshi*; Kanemura, Takuji*; Kondo, Hiroo; Miyashita, Makoto; Nakamura, Hiroo; Sugiura, Hirokazu*; et al.
Journal of Nuclear Materials, 417(1-3), p.1294 - 1298, 2011/10
Times Cited Count：4 Percentile：32.48(Materials Science, Multidisciplinary)Engineering Validation and Engineering Design Activities (EVEDA) of the International Fusion Materials Irradiation Facility (IFMIF) was started. As a Japanese activity for the target system, EVEDA Lithium Test Loop simulating hydraulic and impurity conditions of IFMIF is under design and preparation for fabrication. Feasibility of thermo-mechanical structure of the target assembly and the replaceable back-plate made of F82H (a RAFM) and 316L (a stainless steel) is a key issue. Toward final validation on the EVEDA loop, diagnostics applicable to a high-speed free-surface Li flow and hot traps to control nitrogen and hydrogen in Li are under tests. For remote handling of target assemblies and the replaceable back-plates activated up to 50 dpa/y, lip weld on 316L-316L by laser and dissimilar weld on F82H-316L are under investigation. As engineering design of the IFMIF target system, water experiments and hydraulic/thermo-mechanical analyses of the back-plate are going.
Kondo, Hiroo; Furukawa, Tomohiro; Hirakawa, Yasushi; Ida, Mizuho; Matsushita, Izuru*; Horiike, Hiroshi*; Kanemura, Takuji; Sugiura, Hirokazu*; Yagi, Juro*; Suzuki, Akihiro*; et al.
Journal of Engineering for Gas Turbines and Power, 133(5), p.052910_1 - 052910_6, 2010/12
Times Cited Count：7 Percentile：38.67(Engineering, Mechanical)As a major Japanese activity for the IFMIF/EVEDA, EVEDA Li Test Loop (ELTL) to simulate hydraulic and impurity conditions of IFMIF is under design and preparation for fabrication. Feasibility of hydraulic stability of the liquid Li target and the purification systems of hot traps are major key issues to be validated. This paper presents the current status of the design and construction of the EVEDA Li Test Loop. Detail designs of the loop components such as the target assembly, tanks, an electro-magnetic pump and flow meter and a cold trap for purification system are described in addition to the flow diagnostics system and the hot traps.
Kondo, Hiroo; Furukawa, Tomohiro; Hirakawa, Yasushi; Nakamura, Hiroo*; Ida, Mizuho; Watanabe, Kazuyoshi; Miyashita, Makoto*; Horiike, Hiroshi*; Yamaoka, Nobuo*; Kanemura, Takuji; et al.
Proceedings of 23rd IAEA Fusion Energy Conference (FEC 2010) (CD-ROM), 8 Pages, 2010/10
The Engineering Validation and Engineering Design Activity (EVEDA) for the International Fusion Materials Irradiation Facility (IFMIF) is proceeded as one of the ITER Broader Approach (BA) activities. The EVEDA Li test loop (ELTL) is aimed at validating stability of the Li target and feasibility of a Li purification system as the key issues. In this paper, the design of the ELTL especially of a target assembly in which the Li target is produced by the contraction nozzle is presented.
Kondo, Hiroo; Furukawa, Tomohiro; Hirakawa, Yasushi; Matsushita, Izuru*; Ida, Mizuho; Horiike, Hiroshi*; Kanemura, Takuji; Sugiura, Hirokazu*; Yagi, Juro*; Suzuki, Akihiro*; et al.
Proceedings of 18th International Conference on Nuclear Engineering (ICONE-18) (CD-ROM), 9 Pages, 2010/05
IFMIF is a neutron source aimed at producing an intense high energy neutron flux for testing candidate fusion reactor materials. Under Broader Approach activities, Engineering Validation and Engineering Design Activities (EVEDA) of IFMIF started on July 2007. Regarding to the lithium (Li) target facility, design and construction of EVEDA Li Test Loop is a major activity and is in progress. The detail design was started at the early 2009. Fabrication of the loop was started at middle of 2009, and completion is planned at the end of Feb. 2011.
Yamasaki, Chisato*; Murakami, Katsuhiko*; Fujii, Yasuyuki*; Sato, Yoshiharu*; Harada, Erimi*; Takeda, Junichi*; Taniya, Takayuki*; Sakate, Ryuichi*; Kikugawa, Shingo*; Shimada, Makoto*; et al.
Nucleic Acids Research, 36(Database), p.D793 - D799, 2008/01
Times Cited Count：52 Percentile：71.15(Biochemistry & Molecular Biology)Here we report the new features and improvements in our latest release of the H-Invitational Database, a comprehensive annotation resource for human genes and transcripts. H-InvDB, originally developed as an integrated database of the human transcriptome based on extensive annotation of large sets of fulllength cDNA (FLcDNA) clones, now provides annotation for 120 558 human mRNAs extracted from the International Nucleotide Sequence Databases (INSD), in addition to 54 978 human FLcDNAs, in the latest release H-InvDB. We mapped those human transcripts onto the human genome sequences (NCBI build 36.1) and determined 34 699 human gene clusters, which could define 34 057 protein-coding and 642 non-protein-coding loci; 858 transcribed loci overlapped with predicted pseudogenes.
Aoto, Kazumi; ; ; ; ; Hirakawa, Yasushi
PNC TN9450 97-016, 860 Pages, 1997/06
This report describes the check of the thermocouple well at the inlet of the intermediate heat exchanger(IHX) of C-loop of the secondary heat transfer system of the prototype fast breeder reactor Monju, regarding the sodium leak accident of the thermocouple well at the outlet of the IHX of the same loop of the secondary heat transfer system of the same plant Monju. Various tests and inspections were performed to check damages at the part with rapid diameter change of the thermocouple well where stress concentration may occur, and to get the information about the integrity of the welded part between the thermocouple well and the attachment. The thermocouple well, the rapid diameter change part, larger and smaller part, respectively, of the thermocouple well, and welded part between the thermocouple well and the attachments were examined as written below. (1)Accurate measurement of the dimension. (2)Vibration test by tapping the thermocouple well. (3)Non destructive testing at some points. (4)Chemical composition analysis. (5)Microscopic observation of metalogical structure. (6)Detailed observation around the rapid diameter change part. (7)Hardness test. (8)Research on corrosion at the clearance. (9)Structure strength test of the thermocouple well. (10)Bending test of the thermocouple's sheath at high temperature.
Aoto, Kazumi; ; ; ; ; Hirakawa, Yasushi
PNC TN9420 97-007, 786 Pages, 1997/06
PNC-TN9420-97-007.pdf:311.86MB
The results of the research on the damaged thermocouple well which caused the sodium leak accident at the outlet of the C-loop intermidiate heat exchanger (IHX) of the secondary heat transfer system of the prototype fast breeder reactor Monju are described in this report. A lot of tests, inspections, observations and measurements were carried out to confirm that the thermocouple well and its attachments to the pipe including welded part are normal by checking the possibility of weld failure or corrosion at the clearance which may cause the damage of the thermocouple well, and to get information of the dimensions relating the estimation of the leaked sodium volume and the leakage path, etc. These tests, etc., were performed for the thermocouple well except the fractured surface, the thermocouple well, the welded parts between the thermocouple well and the attachment, and between the attachment and the outlet pipe, etc., as written below. (1)Accurate measurement of the dimension. (2)Inspection to check the fixing condition between the thermocouple well and the attachment. (3)Measurement of the residual stress. (4)Non destructive testing at some points. (5)Chemical composition analysis. (6)Microscopic observation of metalogical structure at the welded part. (7)Hardness test. (8)Research on corrosion at the clearance. (9)Structure strength test of the thermocouple well. (10)Bending test of the thermocouple's sheath at high temperature.
Aoto, Kazumi; ; ; ; ; Hirakawa, Yasushi
PNC TN9410 97-076, 29 Pages, 1996/06
This report describes the check of the thermocouple well at the inlet of the intermediate heat exchanger (IHX) of C-loop of the secondary heat tansfer system of the prototype fast breeder reactor Monju, regarding the sodium leak accident of the thermocouple well at the outlet of the IHX of the same loop of the secondary heat transfer system of the same plant Monju. Various tests and inspections were performed to check damages at the part with rapid diameter change of the thermocouple well where stress concentration may occur, and to get the information about the integrity of the welded part between the thermocouple well and the attachment. The thermocouple well, the rapid diameter change part, larger and smaller part, respectively, of the thermocouple well, and welded part between the thermocouple well and the attachments were examined as written below. (1)Accurate measurement of the dimension. (2)Vibration test by tapping the thermocouple well. (3)Non destructive testing at some points. (4)Chemical composition analysis. (5)Microscopic observation of metalogical structure. (6)Detailed observation around the rapid diameter change part. (7)Hardness test. (8)Research on corrosion at the clearance. (9)Structure strength test of the thermocouple well. (10)Bending test of the thermocouple's sheath at high temperature.
U and 
ThBaba, Mamoru*; *; *; *; *
JAERI-M 89-143, 55 Pages, 1989/10
no abstracts in English
; ;
Nihon Genshiryoku Gakkai-Shi, 20(4), p.236 - 240, 1978/04
Times Cited Count：0no abstracts in English
Nakamura, Kazuyuki; Ida, Mizuho; Kondo, Hiroo; Watanabe, Kazuyoshi; Furukawa, Tomohiro; Hirakawa, Yasushi; Horiike, Hiroshi*; Fukada, Satoshi*; Terai, Takayuki*; Tsuji, Yoshiyuki*; et al.
no journal, ,
IFMIF/EVEDA started at July in 2007. Li Target System consists of five validation tasks (LF1-5) and one design task (LF6). Present status of Li Test Loop Construction and Operation task (LF1) is to complete the fabrication and installation of the almost key components except Target Assembly and Two types of traps for nitrogen and hydrogen, and to continue the connection with the components by the pipes. In the Diagnostics task (LF2), the characterization of the contact probe level meter is on going in Osaka University. In the Purification System task (LF4), the characterization of the Fe-Ti gettering material in Tokyo University and of Y gettering material in Kyushu University is on going. In the Remote Handling task (LF5), the design of the experimental facility has been finished. In the Engineering Design task (LF6), the engineering design for the IFMIF will be completed based on the validation tasks (LF1-5).
Kondo, Hiroo; Furukawa, Tomohiro; Hirakawa, Yasushi; Iuchi, Hiroshi; Nakamura, Kazuyuki; Ida, Mizuho; Wakai, Eiichi; Watanabe, Kazuyoshi; Kanemura, Takuji; Horiike, Hiroshi*; et al.
no journal, ,
The International Fusion Materials Irradiation Facility (IFMIF) is a neutron source aimed at producing an intense high energy neutron flux for testing candidate materials to be used in the fusion demonstration reactor. Engineering Validation and Engineering Design Activities (EVEDA) on IFMIF started under Broader Approach. As a major Japanese activity for Li target tasks of EVEDA, EVEDA Li Test Loop is under construction. Feasibility of hydraulic stability of the Li target and purification systems of hot traps is major key issues to be validated. Toward the validation at the loop, laboratory-scale tests and design for diagnostics to the high-speed free-surface Li target and the hot traps to control nitrogen and hydrogen in Li are carried out along with the construction of the loop. Regarding to progress of the construction, all major components except a target assembly are installed in a mount of the loop. The construction is scheduled to be finished on Feb. 2011.
modelTakahashi, Momoko; Noguchi, Miho; Hirakawa, Hirokazu*; Okayasu, Ryuichi*
no journal, ,
Ionizing radiation has been widely used as a tool for tumor treatment. However, there are still difficulties to treat the solid tumor with only irradiation. Several studies have been shown that the combination therapy using both X-irradiation and antitumor drug is more effective to tumor compared with X-irradiation only. Previously Noguchi et al. showed the Hsp90 inhibitor 17AAG induced tumor cell death effectively with X-irradiation. Hsp90 is the enzymes activated by cellular stress and activates several tumor-related genes. To clarify whether or not the combination therapy of carbon ion beam and 17AAG is effective to solid tumors, we tested the growth of solid tumor with the combination of X-irradiation and 17AAG and compared the results from 
study.
Nakamura, Kazuyuki; Ida, Mizuho; Kanemura, Takuji; Kondo, Hiroo; Niitsuma, Shigeto; Hirakawa, Yasushi; Furukawa, Tomohiro; Watanabe, Kazuyoshi; Horiike, Hiroshi; Terai, Takayuki*; et al.
no journal, ,
Three and half years has been passed from the start of IFMIF/EVEDA. In IFMIF/EVEDA, tasks for Lithium Target System consists of 5 validation tasks (LF1-5) and a design task (ED3), and are shared by Japan and Europe. Japan is covering the construction and operation of EVEDA Li Test Loop (LF1), diagnostics (LF2), purification system (LF4), remote handling system (LF5) and engineering design (ED3) with the contribution from universities. The present status of these tasks will be reported in the conference.
