The Effects of essence of chicken on the trace metal distribution in stressful mice brain slices by in-air micro-PIXE

大気マイクロPIXEを用いたストレスを受けたマウスの脳切片中の微量金属分布測定によるチキンエキスの効果

櫻井 映子*; 谷内 一彦*; 石井 慶造*; 藤木 広太*; 平石 慎吾*; 山崎 浩道*; 松山 成男*; 岡村 信行*; 横山 彰人; 加田 渉; 江夏 昌志; 佐藤 隆博; 神谷 富裕

Sakurai, Eiko*; Yanai, Kazuhiko*; Ishii, Keizo*; Fujiki, Kota*; Hiraishi, Shingo*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Okamura, Nobuyuki*; Yokoyama, Akihito; Kada, Wataru; Koka, Masashi; Sato, Takahiro; Kamiya, Tomihiro

We examined the effects of essence of chicken (BEC) on stressful H3-KO mice and distribution changes of trace metal in the brain using micro-PIXE. The mice were administered orally1 ml of BEC before subjected stress. The amount of Zinc in the slices of subjected restraint stress (physical stress) or no-stress control group are almost same when compared with BEC treated group. However, the amount of zinc in the BEC treated slice of subjected psychological stress were significant higher than that of no-treated BEC mice. Bromine level in the brain of BEC treated mice slightly-higher than non-treated mice (Data was not shown). Zinc levels show tended correlation with iron in BEC treated psychological-stress mice brain. BEC might have increased blood flow and the produce anti-stress effect.